Moreover, 11β-PGF2α titers correlated with basopenia (Spearman r = −0.2585, P = 0.0169) and CD203c expression on SLE basophil (Spearman r = 0.3695, P < 0.0001) (Fig. 1h and Supplementary Fig. 2a,b). Here, ENPP3 is linked to systemic lupus erythematosus.