In terms of the activation/expression of receptors and signaling pathways in response to C. glabrata sensing and colitis, MBL-C and Myd88 expression increased significantly, while the expression of TLR-4 and PPARγ decreased in the colons in response to C. glabrata ΔChs3 (Supplementary data Fig. 5). The gene discussed is PPARG; the disease is colitis.