MAPK14 and neoplasm: p38 can be activated by tyrosine kinase receptors (PDGF receptor, VEGF receptor, EGF receptor, FGFR1) to function as a positive regulator of tumor progression, mediating motility and invasion, suppressing apoptosis, stimulating the epithelial‐to‐mesenchymal transition in various cell types (Bates & Mercurio, 2003; Frey et al, 2004; Nishihara et al, 2004).