HOTAIR and cancer: Previously, there have been several meta-analysis [39–41] to pool eligible studies to examine the relationship between cancer risk and HOTAIR polymorphisms (including rs920778, rs4759314, rs7958904, rs874945, and rs1899663), and most of which included all studies and did not take into account the rejection of studies that the genotype distribution of controls did not conform to the HWE except Lv et al.’s study [42].