KRAS and colorectal carcinoma: Work using a yeast strain lacking RAS2 and transformed with either KRASwt or its most common mutated alleles (KRASG13D, KRASG12D, KRASG12V) in colorectal carcinoma made it possible to uncover that the activating KRAS mutations, unlike wild-type KRAS, increase the level of the yeast autophagy reporter Atg8 [17].