A significant positive association was detected between MMP-1 immunoreactivity and smoking status (p = 0.016), Brinkmann index (p = 0.038), pathological T factor (pT) (p = 0.029), tumor size (p = 0.007), and subtype of invasive mucinous adenocarcinoma (p < 0.001). Here, MMP1 is linked to neoplasm.