TERT and laryngeal neoplasm: TERT promoter mutations alone have been linked with worse prognosis in various tumor entities such as melanoma [60,61], glioblastoma multiforme [13], medulloblastoma [62], urogenital cancer [63,64], laryngeal tumors [65], and with larger tumors and lymph node metastasis in the case of conventional papillary thyroid carcinomas [12,66,67,68].