A recent study demonstrated that R1 and EVER2 proteins found in epidermodysplasia verruciformis (EV) patients with high susceptibility to papillomaviruses causing skin cancer interact with ZnT1 to control the zinc balance in keratinocytes, suggesting the importance of maintaining intracellular zinc homeostasis in skin cancer induced by viral infection [70]. The gene discussed is SLC30A1; the disease is skin cancer.