VEGFA and liver dysplastic nodule: Glomerular samples from DN patients have shown an increase in the expression of VEGF-Axxx mRNA relative to VEGF-Axxxb mRNA during the later stages of DN, when the kidney function has declined; however, during the early stages of DN, when the kidney is functioning relatively normally, there is an increase in the VEGF-Axxxb/VEGF-Axxx ratio [9].