LPKO viruses show delayed LMP gene activation, but the inference that the deregulation of LMPs in LPKO may be responsible for the death of naïve B cells is countered by the observation that this death mainly manifests around 10–14 days post infection, by which time LMP transcripts in LPKO infections are approaching wild-type levels (Fig 7). This evidence concerns the gene PDLIM7 and infection.