Moreover, we substantiate the proposed specific associations between 5p15.33 (rs10069690) and 20q13.33 (rs2297440) variants with TERT promoter mutations, 9p21.3 (rs634537) with TERT-only glioma, as well as 17p13.1 (rs78378222) with TERT-IDH glioma. Here, TERT is linked to central nervous system cancer.