At 2q33.3 we detected a significant Hi-C interaction between the glioma risk SNP rs7572263 and IDH1/IDH1-AS1. Overexpression of IDH1 mutant proteins has been reported to sensitize glioma cells to radiation [29], providing an interesting mechanism to test the allele-specific effects of this SNP. Here, IDH1 is linked to central nervous system cancer.