In addition, we found strong associations with IDH wild-type gliomas at 5p15.33 (rs10069690), 7p11.2 (rs75061358), 9p21.3 (rs634537), and 20q13.33 (rs2297440) (Supplementary Fig. 5 [Online Resource 1], Supplementary Table 3 [Online Resource 2]). This evidence concerns the gene IDH2 and central nervous system cancer.