By contrast, in L. mexicana-infected mice, another model for non-healing cutaneous leishmaniasis, the lesion development and parasite burden were comparable in WT and IFNAR−/− mice on a mixed 129Sv/C57BL/6 background, with only a transient defect of the production of IFN-γ and IL-10 upon in vitro restimulation of lymph node T cells (92). The gene discussed is IFNG; the disease is cutaneous leishmaniasis.