Significant genotypic association was identified between NEURL SNP rs6584555 and AF under all three models, although most significant associations were obtained under the dominant and recessive models before and after adjusting for covariates of age, gender, HTN, DM and CAD (Pobs = 4.03 × 10−4, Padj = 4.85 × 10−5 under an additive model; Pobs = 4.38 × 10−4, Padj = 4.26 × 10−4 under a dominant model; Pobs = 5.3 × 10−3, Padj = 1.51 × 10−3 under a recessive model) (Table 3). The gene discussed is NEURL1; the disease is atrial fibrillation.