CD19 and acute lymphoblastic leukemia: As showed in the Fig. 1, the 1928zT2 T cells generated from PBMC of ALL patient lysed more than 75% CD19-expressing NALM-6 cells at all indicated E:T ratios from 1:1 to 1:16, whereas less than 50% NALM-6 target cells were killed by 1928z T cells at E:T ratio of 1:16, indicating that the cytotoxicity of 1928zT2 T cells against target cells is more potent than that of 1928z T cells.