The hazard ratios (95% confidence intervals) per 1-log NT-proBNP calculated using multivariate Cox analysis were: all causes of death, 3.83 (2.51–5.85); CVD-related, 4.30 (2.12–8.75); infection and malignancy-related, 2.41 (1.17–4.93); and others and unknown cause of death, 5.63 (2.57–12.37). The gene discussed is NPPB; the disease is infection.