KLK1 and ganglioneuroma: In order to determine the effects of KKS in modulating Type I IFN responses, we tested the BKs which are central in the KKS system (1, 21, 58), tissue klk1 which has been shown to ameliorate GN in antibody-mediated kidney disease (12) and captopril, a widely prescribed ACEi (10, 59).