We detected a number of CD68+ macrophages in the spleen of both tumor-bearing HSC-NOG-hIL-6 Tg and HSC-NOG non-Tg mice, with greater numbers detected in HSC-NOG-hIL-6 Tg mice than in HSC-NOG non-Tg mice (Figures 5B,C). The gene discussed is CD68; the disease is neoplasm.