MLKL and infection: Bacteria loads in feces of both WT and MLKL−/− mice were comparable at 6 h p.i. (p = 0.4954, Figure 5F), like those at 48 h p.i. Although no viable bacteria were detected in the liver and spleen of mice at this early stage of infection, we noted that a 0.5–1 Log increase in bacterial numbers was detected in cecum (p = 0.0742) and MLN tissues (p = 0.1456) of MLKL−/− mice compared with WT mice (Figures 5G,H).