Quantitative analysis of MG-H1 residue content of rat liver protein suggests relatively high steady-state levels are maintained in health, 3.3 mmol/mol arginine; therefore, GLO1 deficiency in NAFLD may overwhelm the hepatic capacity for removal of MG-H1-modified proteins contributing to NAFLD progression as suggested by our results. The gene discussed is MGAM; the disease is metabolic dysfunction-associated steatotic liver disease.