ALK and non-small cell lung carcinoma: A phase I clinical trial (NCT01579994) evaluated ganetespib at 3 doses (100 mg/m2, 150 mg/m2 and 200 mg/m2) administered on day 1 and 8 of a 21-day cycle, in combination with crizotinib (250 mg twice daily, continuously) in twelve ALK-rearranged, ALK inhibitor-naïve patients with metastatic NSCLC.