The initial trial of ganetespib in NSCLC was a phase II study involving 99 patients with previously treated NSCLC and three molecular cohorts, including EGFR-mutated (N = 15), KRAS mutated (N = 17) and EGFR/KRAS wild type (N = 66). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.