Available literature reveals that TNK1 has both tumor suppressing and oncogenic potential as it can mitigate the growth of tumor cells by dowenregulating Ras-Raf1-MAPK pathway [95], induce apoptosis through NF-κB inhibition [96], activate cellular transformation and growth of neoplastic cells [97, 98]. The gene discussed is NFKB1; the disease is neoplasm.