KRAS and non-small cell lung carcinoma: Phase I and II clinical trials using MEK inhibitors in combination with other therapies are still recruiting patients or under evaluation in KRAS-mutated NSCLC (NCT02964689 evaluating binimetinib in addition to standard chemotherapy; NCT01859026 studying MEK162 in combination with erlotinib; NCT02022982 investigating palbociclib and PD-03259019).