Overexpression of the PTK gene enhances the activity of PTK and changes its downstream signaling pathways, causing cell proliferation disorders and eventually leading to tumor formation [5]; mutations in tumor tissue may cause PTK to spontaneously activate in the absence of a stimulus source or appear abnormal growth rate [24]; clinical studies have shown that PTK overexpression or decreased expression can show the biological characteristics of the tumor or predict the response to treatment and survival [25]. This evidence concerns the gene PTK2B and neoplasm.