PDGFRA and esophageal squamous cell carcinoma: Mutations in the PDGFRα gene have been found in 5% of gastrointestinal stromal cancer (GIST) and amplifications of PDGFRα were reported in 5–10% of glioblastoma multiforme, in oligodendrocytoma, esophageal squamous cell carcinoma and artery intimal sarcomas [4].