Interestingly, using a METi-sensitive SNU5 and METi-resistant SNU1 gastric cancer cell lines, expression of several glycolysis-related mitochondrial enzymes, such as voltage-dependent anion-selective channel protein 1 (VDAC1) and adenine nucleotide translocase 2 (ANT2), was significantly regulated in response to MET inhibitor PHA665752 [55]. The gene discussed is VDAC1; the disease is gastric cancer.