Dasatinib, another BCR-ABL and also a Src family tyrosine kinase inhibitor was approved by the FDA as an important strategy for the treatment of patients with newly diagnosed chronic-phase CML and for imatinib-resistant or -intolerant patients with CP or advanced-phase CML or Ph + ALL [143]. This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.