Ma et al. [47] found that miR-26a can inhibit the EMT by down regulation of EZH2 expression, Liang et al. [48] found that miR-26a can regulate the biogenesis of let-7d, and Slaby et al. [49] had proved that miR-26a was associated with tumor relapse in renal cell carcinoma, which all corresponds well with the expression pattern of miR-26a in our study. This evidence concerns the gene EZH2 and hereditary clear cell renal cell carcinoma.