In the current study, we showed that the DOCK7 rs1748195 SNP and rs1748195G-rs12563308T haplotype were associated with an increased risk of CAD and the severity to coronary atherosclerosis, whereas the ANGPTL3 rs12563308 SNP was associated with a decreased risk of CAD. The gene discussed is ANGPTL3; the disease is coronary artery disorder.