A comparison of the 44 differently expressed genes with the gene expression patterns of distinct melanoma cell phenotypes as determined by Hoek et al. (invasive or proliferative, [48]) revealed an overlap of three genes (cysteine-rich, angiogenic inducer, 61 (CYR61), angiopoietin-like 4 (ANGPTL4), and inhibin beta A (INHBA)). The gene discussed is CCN1; the disease is melanoma.