In this study, we investigated the effects of the alternative expression of the T or sT antigens on the ability of BC cells to activate macrophages in response to BCG challenge and on the transcriptome of BC cells, utilizing the HT1376 cell line in which the T antigen was replaced by the sT antigen, by retroviral transduction with the ST3GAL1 cDNA. Here, ST3GAL1 is linked to breast cancer.