In two studies, breast cancers with BRCA1-like signature, as defined as BRCAness of the BRCA1 gene were found in 18% of breast cancers and showing a better response to anthacyline-based or platin containing high-dose chemotherapies (Lips et al. 2017; Vollebergh et al. 2014). The gene discussed is BRCA1; the disease is breast cancer.