Additionally, using The Cancer Genome Atlas (TCGA) urothelial bladder carcinoma cohort41, we quantified ALCAM isoform expression in human bladder tumors and showed that, ALCAM-Iso2 is expressed two-fold higher than ALCAM-Iso1 (P < 0.0001, Fig. 7c, right panel). Here, ALCAM is linked to urinary bladder neoplasm.