HPGDS and early-onset autosomal dominant Alzheimer disease: Eukaryotic GSTs have garnered much attention due to their implications in mammalian disease states such as Parkinson’s and Alzheimer’s disease[3,6,7] and their ability to detoxify electrophilic toxins such as carcinogens[8] and cancer drugs[9], while bacterial GSTs have been implicated in antibiotic resistance, isomerization reactions, and bioremediation[10].