Although miR‐365 has been shown to repress bcl‐2 expression in cancer cells and human umbilical vein endothelial cells (HUVECs; Nie et al., 2012; Qin et al., 2011), we still need to determine whether miR‐365 would modulate bcl‐2 expression in adult rat brain after ischemic stroke. This evidence concerns the gene BCL2 and ischemic stroke.