In the case of increased expression of CCT4 (Chaperonin Containing TCP1 subunit 4) in adipose tissue of patients with FPLD it can be characterized by the necessity of raising the recovery rate of malformed proteins due to ERS, because these chaperones have the function of assisting the correct folding of proteins by ATP hydrolysis [39, 40]. The gene discussed is CCT4; the disease is familial partial lipodystrophy.