The CARD9/Bcl-10/MALT1 complex in Dectin-1 signaling upon Candida infection has been known to activate the IKK complex, leading to the phosphorylation of IκB and the activation of all canonical NF-κB subunits including p50, p65, and c-Rel (24, 51, 138). Here, NFKB1 is linked to candidiasis.