Likewise, we previously reported that pan-HDAC inhibition attenuates renal growth in early experimental diabetes; a finding that we attributed to downregulation of the epidermal growth factor receptor (EGFR) (Gilbert et al., 2011), which may itself be regulated by HDAC6 (Deribe et al., 2009; Gao et al., 2010). The gene discussed is HDAC6; the disease is diabetes mellitus.