KCNH2 and torsades de pointes: Here we have developed CHARMM generalized force field (CGENFF) (Vanommeslaeghe et al., 2010) parameters for the hERG blocker d-sotalol, which has high cardiotoxic risk (Colatsky et al., 2016) for the ventricular tachycardia characterized by Torsades de Pointes (TdP) arrhythmias (Waldo et al., 1996; Yap and Camm, 2003).