GRIA2 and ischemia: Taken together, it is possible that the initial influx of calcium through homomeric GluA1-containing AMPARs may induce signaling pathways that facilitate the stabilization or expression of GluA2-containing AMPARs, which may then contribute to neuronal survival following ischemia as has been previously reported (Liu et al., 2004; Henley and Wilkinson, 2016).