However, rs9530458 is in low LD (r2 = 0.14) with rs11841001 (P = 0.06 in the OAG and CA analysis in Europeans), suggesting that even if the LMO7 gene affects glaucoma as well as corneal astigmatism, this effect may come from independent risk variants within LMO7. On the other hand, the MYOF and XRCC6P1 locus is ~1 Mb away from PLCE1, a known risk locus for VCDR. Here, PLCE1 is linked to glaucoma.