BPIFA1 and respiratory tract infectious disorder: The loss of bpifa1 has previously been shown to predispose mice more severe respiratory infections following an experimental challenge and yet we found that IN challenge of Bpifa1−/− mice with the major otopathogen NTHi, did not result in significant ME infection, although our data did appear to suggest that Bpifa1−/− mice infection prevalence was marginally higher.