AGO1 and cancer: In agreement with current paradigms of cancer gene activity30 and further implicating a relevance of altered miR/siRNA processing factors in T-PLL, we identified uniparental disomies (UPDs) of AGO1/-3/-4 (all on chr.1) in 68.7% of cases (n = 57/83; against HapMap; Supplementary Data 7).