Indeed, results from gene set enrichment analysis (GSEA) revealed that both SREBP1 (gene name: SREBF1) and SREBP2 (gene name: SREBF2) expression was positively associated with not only lipid biosynthesis pathways but also glucose metabolism and TCA cycle in CRC patients (Supplemental Figure S4). The gene discussed is SREBF1; the disease is colorectal carcinoma.