MEG3 and neoplasm: As shown in Fig. 2a–c, when MEG3 was overexpressed, the xenograft tumor weight decreased approximately one-third compared to the corresponding control group (0.22152 ± 0.07382 g versus 0.07042 ± 0.0652 g, P = 0.004061372 <0.01); when MEG3 was overexpressed, the xenograft tumor size decreased approximately one-fifth compared to the corresponding control group (0.15508 ± 0.1035 cm3 versus 0.03125 ± 0.05229 cm3, P = 0.007228 <0.01).