Bollu et al (2015) reported findings similar to ours that FASN‐dependent palmitoylation positively regulates EGFR and supports cancer cell growth whereas Runkle et al (2016) showed that palmitoylation suppresses EGFR signaling by “pinning” the C‐terminal tail of the receptor to the plasma membrane. The gene discussed is EGFR; the disease is cancer.