FASN and cancer: FASN is crucial for cancer cell survival, and its overexpression has been associated with poor prognosis, higher risk of cancer recurrence, and drug resistance, in colon and ovarian cancer, breast and renal cell carcinomas (Alo’ et al, 1996; Gansler et al, 1997; Horiguchi et al, 2008; Liu et al, 2008; Ogino et al, 2008).