GoF SAMD9 mutations cause MIRAGE (myelodysplasia, infection, restriction of growth, adrenal hypoplasia, genital phenotypes, and enteropathy) disorder [29], while GoF SAMD9L mutations cause a similar disorder characterized with cytopenia, immunodeficiency, and neurological symptoms [19, 30]. The gene discussed is SAMD9; the disease is immunodeficiency disease.