Other factors previously associated with AKI include vasopressor use, mechanical ventilation, high APACHE II score, severe acidosis, high levels of C-reactive protein and lactic dehydrogenase upon ICU admission, longer stays in the ICU [17], high body mass index, history of asthma [3], high SOFA score, and greater incidence of shock, multiorgan dysfunction syndrome and coinfection [18]. The gene discussed is CRP; the disease is asthma.