Moreover, in a study with a total of 401 Chinese NSCLC patients (280 males and 121 females) investigating the correlation between EGFR mutations and incidence of distant metastases and tumor size in patients with non-small-cell lung cancer, the tumor size in EGFR mutation group was significantly smaller than that in the wild-type group (p< 0.001), as shown in our study [38]. The gene discussed is EGFR; the disease is neoplasm.