In relation to the observed pathway enrichment, Xiong et al. [70] showed that the activation of LXR induced the expression of Socs3, and to illustrate a potential dual anti-inflammatory and anti-angiogenic property of Socs3, Stahl et al. [71] showed Socs3 to have inhibitory effects on pathologic angiogenesis in murine models of oxygen-induced retinopathy and cancer. Here, SOCS3 is linked to cancer.