CDKN2A and coronary artery disorder: In a study by Visel et al. (142), the results provide direct evidence that the coronary artery disease risk interval has a crucial role in regulation of cardiac Cdkn2a/b expression (a mouse ortholog of the 9p21 locus) and suggest that this region has an effect on the progression of coronary artery disease by modifying the dynamics of vascular cell proliferation.